De Lisio Lab
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The De Lisio lab at the University of Ottawa is recruiting Doctoral and Postdoctoral candidates interested in cellular and molecular exercise physiology. Work in the De Lisio lab is focused on answering two main questions: (1) What are the external cues that regulate the cellular composition of the stem cell niche, and (2) How do changes in the cellular composition of the stem cell niche regulate stem cell function? To answer these questions, we take an interdisciplinary approach combining in vitro and animal models with human studies, and apply techniques ranging from molecular biology to systems physiology. We focus on stem cell-niche interactions in skeletal muscle and bone marrow in the context of exercise, obesity, and cancer. Our goal is to optimize endogenous stem cell function to maintain tissue health across the lifespan. Current projects include:
  • The role of exercise/mechanical forces in regulating the mesenchymal stromal cell secretome.
  • Radiation-induced fibrosis in skeletal muscle.
  • Systemic effects of obesity-induced myelopoiesis.

The lab is located within the Faculty of Health Sciences’ newly renovated, state-of-the-art “Integrative Health Biology Lab” at Roger Guindon Hall. Our lab’s affiliations with the University of Ottawa Brain and Mind Institute, Regenerative Medicine Program, and Centre on Neuromuscular Disease provide excellent opportunities for collaboration and career development.

The successful candidate will be expected to lead an independent research project, supervise a team of graduate and undergraduate researchers, and disseminate their findings to the broader research community. Experience with cell/molecular biology techniques, animal models, and/or human interventions is desired.
Interested applicants should contact Dr. De Lisio directly (see Contact Tab) with a CV, list of references, unofficial transcript, and one-page statement of research interests.
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